Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839524 | 1.00 | BRPF1 (0.51) | BRPF1MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL1841666 | 1.00 | BRPF1 (0.51) | BRPF1MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL1839961 | 1.00 | BRPF1 (0.51) | BRPF1MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL1839569 | 0.90 | BRPF1 (0.54) | BRPF1MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL1843146 | 0.90 | BRPF1 (0.54) | BRPF1MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL1838548 | 0.89 | BRPF1 (0.55) | BRPF1MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL1841352 | 0.88 | BRPF1 (0.49) | BRPF1MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL1838653 | 0.87 | BRPF1 (0.51) | BRPF1MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL1841353 | 0.87 | BRPF1 (0.51) | BRPF1MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL14217658 | 0.81 | BRPF1 (0.54) | BRPF1MEN1PKMKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964732-B2 | Substituted bicyclocarboxyamide compounds | PFIZER INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20100267769-A1 | Substituted Bicyclocarboxyamide Compounds | Pfizer, Inc. and Renovis Inc. | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267769-A1 | Substituted Bicyclocarboxyamide Compounds | TRPV1, OPRL1, CNR1 | BRPF1 1691/4885MEN1 4680/4885PKM 2806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.