SCHEMBL14217670

SCHEMBL14217670

CCc1noc(-c2ncn3c2CN=C(c2ccccc2)c2cc(C)ccc2-3)n1

nearest known ligand 0.82

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRG2 P18507 1/20 0.62
GABRB3 P28472 1/20 0.62
GABRA3 P34903 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8229824 0.92 GABRG2 (0.63) GABRG2GABRB3GABRA3
SCHEMBL7717825 0.90 GABRG2 (0.62) GABRG2GABRB3GABRA3
SCHEMBL13524265 0.90 GABRG2 (0.62) GABRG2GABRB3GABRA3
SCHEMBL8271852 0.90 GABRG2 (0.62) GABRG2GABRB3GABRA3
SCHEMBL8271855 0.90 GABRG2 (0.60) GABRG2GABRB3GABRA3
SCHEMBL7721886 0.88 GABRG2 (0.81) GABRG2GABRB3GABRA3
SCHEMBL7722027 0.86 GABRG2 (0.66) GABRG2GABRB3GABRA3
SCHEMBL8229905 0.81 GABRG2 (0.62) GABRG2GABRB3GABRA3
SCHEMBL8360445 0.78 GABRG2 (0.80) GABRG2GABRB3GABRA3
SCHEMBL24435640 0.77 GABRA3 (0.85) GABRG2GABRB3GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1925614-A1 Anxiolytic agents with reduced sedative and ataxic effects Wisys Technology Foundation, Inc. (US) 2008-05-28 EP disclosed