Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 13/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14076710 | 0.92 | QPCT (0.48) | QPCTKMT2AQPCTL | |
| SCHEMBL5056669 | 0.92 | QPCT (0.48) | QPCTKMT2AQPCTL | |
| SCHEMBL16472234 | 0.89 | PIK3CD (0.32) | QPCT | |
| SCHEMBL5056876 | 0.83 | QPCT (0.41) | QPCTQPCTL | |
| SCHEMBL14217791 | 0.83 | QPCT (0.41) | QPCTQPCTL | |
| SCHEMBL14076605 | 0.81 | QPCT (0.35) | QPCT | |
| SCHEMBL5053565 | 0.81 | QPCT (0.36) | QPCTQPCTL | |
| SCHEMBL14076609 | 0.80 | QPCT (0.51) | QPCTQPCTL | |
| SCHEMBL5062254 | 0.80 | QPCT (0.51) | QPCTQPCTL | |
| SCHEMBL14076518 | 0.80 | PIK3CD (0.32) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091945-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2014-01-15 | — | — | EP | disclosed |
| WO-2008055947-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-05-15 | — | — | WO | disclosed |