Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
| ▸ | TYK2 | P29597 | 2/20 | 0.30 |
| ▸ | JAK3 | P52333 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053565 | 0.93 | QPCT (0.36) | PIK3CDFASNQPCT | |
| SCHEMBL14076518 | 0.91 | PIK3CD (0.32) | PIK3CDFASNTBK1QPCTJAK2 | |
| SCHEMBL14217747 | 0.89 | QPCT (0.41) | QPCT | |
| SCHEMBL5053609 | 0.83 | QPCT (0.44) | QPCT | |
| SCHEMBL14076563 | 0.83 | QPCT (0.44) | QPCT | |
| SCHEMBL14076710 | 0.81 | QPCT (0.48) | QPCT | |
| SCHEMBL5056669 | 0.81 | QPCT (0.48) | QPCT | |
| SCHEMBL5062254 | 0.80 | QPCT (0.51) | QPCT | |
| SCHEMBL14076609 | 0.80 | QPCT (0.51) | QPCT | |
| SCHEMBL14217791 | 0.79 | QPCT (0.41) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091945-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2014-01-15 | — | — | EP | disclosed |