Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPTLC1 | O15269 | 2/20 | 0.72 |
| ▸ | SPTLC2 | O15270 | 2/20 | 0.72 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 11/20 | 0.44 |
| ▸ | ACE | P12821 | 10/20 | 0.44 |
| ▸ | CPA1 | P15085 | 10/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 10/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14190672 | 0.94 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAHMMEACE | |
| SCHEMBL6804868 | 0.94 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAHMMEACE | |
| SCHEMBL14190668 | 0.94 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAHMMEACE | |
| SCHEMBL14217995 | 0.93 | SPTLC1 (0.76) | SPTLC1SPTLC2FAAHMMEACE | |
| SCHEMBL14190628 | 0.93 | SPTLC1 (0.73) | SPTLC1SPTLC2FAAHMMEACE | |
| SCHEMBL6804492 | 0.92 | SPTLC1 (0.72) | SPTLC1SPTLC2FAAHMMEACE | |
| SCHEMBL6805644 | 0.92 | SPTLC1 (0.72) | SPTLC1SPTLC2FAAHMMEACE | |
| SCHEMBL14190644 | 0.91 | SPTLC1 (0.71) | SPTLC1SPTLC2FAAHMMEACE | |
| SCHEMBL14190669 | 0.91 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAHMMEACE | |
| SCHEMBL14190637 | 0.90 | SPTLC1 (0.70) | SPTLC1SPTLC2FAAHMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378446-B2 | Compound having anti-HCV activity and process for producing the same | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-05-27 | — | — | US | disclosed |