Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPTLC1 | O15269 | 2/20 | 0.76 |
| ▸ | SPTLC2 | O15270 | 2/20 | 0.76 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804394 | 0.94 | SPTLC1 (0.78) | SPTLC1SPTLC2FAAHITGB3ITGA2B | |
| SCHEMBL14190676 | 0.94 | SPTLC1 (0.78) | SPTLC1SPTLC2FAAHITGB3ITGA2B | |
| SCHEMBL14190673 | 0.94 | SPTLC1 (0.78) | SPTLC1SPTLC2FAAHITGB3ITGA2B | |
| SCHEMBL14190621 | 0.93 | SPTLC1 (0.77) | SPTLC1SPTLC2FAAHITGB3ITGA2B | |
| SCHEMBL14190624 | 0.93 | SPTLC1 (0.77) | SPTLC1SPTLC2FAAHITGB3ITGA2B | |
| SCHEMBL14217994 | 0.93 | SPTLC1 (0.72) | SPTLC1SPTLC2FAAHITGB3ITGA2B | |
| SCHEMBL10082710 | 0.92 | SPTLC1 (0.76) | SPTLC1SPTLC2FAAHITGB3ITGA2B | |
| SCHEMBL10082708 | 0.92 | SPTLC1 (0.76) | SPTLC1SPTLC2FAAHITGB3ITGA2B | |
| SCHEMBL14190636 | 0.91 | SPTLC1 (0.74) | SPTLC1SPTLC2FAAHITGB3ITGA2B | |
| SCHEMBL14190626 | 0.91 | SPTLC1 (0.74) | SPTLC1SPTLC2FAAHITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378446-B2 | Compound having anti-HCV activity and process for producing the same | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-05-27 | — | — | US | disclosed |