Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2025821 | 0.87 | SCARB1 (0.41) | — | |
| SCHEMBL2025823 | 0.87 | SCARB1 (0.41) | — | |
| SCHEMBL14218049 | 0.87 | ICAM1 (0.32) | ICAM1VCAM1GRIA2 | |
| SCHEMBL16493864 | 0.85 | SRC (0.36) | — | |
| SCHEMBL14218081 | 0.84 | PARG (0.38) | — | |
| SCHEMBL14218044 | 0.83 | PARG (0.38) | ICAM1VCAM1GRIA2 | |
| SCHEMBL14217956 | 0.82 | PARG (0.36) | GRIA2 | |
| SCHEMBL14217955 | 0.82 | PARG (0.36) | GRIA2 | |
| SCHEMBL14217937 | 0.82 | PARG (0.36) | GRIA2 | |
| SCHEMBL14218055 | 0.80 | HTR6 (0.31) | ICAM1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063867-A2 | TETRAHYDROCYCLOPENTA[B] INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-05-29 | — | — | WO | disclosed |