Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14218051 | 0.91 | PLA2G2A (0.38) | PLA2G2AALDH1A1KDM4ELMNACNR2 | |
| SCHEMBL14218054 | 0.91 | PLA2G2A (0.38) | PLA2G2AALDH1A1KDM4ELMNACNR2 | |
| SCHEMBL16493698 | 0.87 | HRH1 (0.46) | PLA2G2AALDH1A1KDM4ELMNAATM | |
| SCHEMBL12579039 | 0.87 | HRH1 (0.46) | PLA2G2AALDH1A1KDM4ELMNAATM | |
| SCHEMBL16493856 | 0.87 | HRH1 (0.46) | PLA2G2AALDH1A1KDM4ELMNAATM | |
| SCHEMBL2022722 | 0.87 | HRH1 (0.46) | PLA2G2AALDH1A1KDM4ELMNAATM | |
| SCHEMBL14217938 | 0.86 | ELANE (0.34) | PLA2G2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16493756 | 0.86 | S1PR3 (0.42) | PLA2G2AALDH1A1KDM4ELMNAATM | |
| SCHEMBL16493758 | 0.86 | S1PR3 (0.42) | PLA2G2AALDH1A1KDM4ELMNAATM | |
| SCHEMBL16493759 | 0.86 | S1PR3 (0.42) | PLA2G2AALDH1A1KDM4ELMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063867-A2 | TETRAHYDROCYCLOPENTA[B] INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-05-29 | — | — | WO | disclosed |