Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HK1 | P19367 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14217935 | 0.91 | DRD2 (0.33) | PTGDR2PARGBCHEACHE | |
| SCHEMBL14217936 | 0.91 | DRD2 (0.33) | PTGDR2PARGBCHEACHE | |
| SCHEMBL2024659 | 0.88 | SCARB1 (0.34) | PTGDR2CYP11B2 | |
| SCHEMBL12579036 | 0.88 | SCARB1 (0.34) | PTGDR2CYP11B2 | |
| SCHEMBL14217996 | 0.86 | PTGDR2 (0.34) | PTGDR2PARGPLA2G2ABCHEACHE | |
| SCHEMBL14218050 | 0.86 | PLA2G2A (0.41) | KDM4ESMN1; SMN2ALDH1A1PLA2G2A | |
| SCHEMBL14624590 | 0.85 | PTGDR2 (0.42) | PTGDR2BCHEACHE | |
| SCHEMBL2023488 | 0.82 | SCARB1 (0.34) | ADORA3PTGDR2PARG | |
| SCHEMBL12579037 | 0.82 | SCARB1 (0.34) | ADORA3PTGDR2PARG | |
| SCHEMBL12579040 | 0.80 | SCARB1 (0.36) | PTGDR2KDM4EPARGALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063867-A2 | TETRAHYDROCYCLOPENTA[B] INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-05-29 | — | — | WO | disclosed |