Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | LSS | P48449 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055450 | 0.91 | TDP1 (0.73) | GAATDP1ALDH1A1PHLPP2KDM4E | |
| SCHEMBL27579412 | 0.89 | TDP1 (0.71) | GAATDP1ALDH1A1PHLPP2KDM4E | |
| SCHEMBL11287086 | 0.86 | GAA (0.71) | GAATDP1ALDH1A1PHLPP2KDM4E | |
| SCHEMBL14218446 | 0.85 | BCHE (0.60) | GAATDP1ALDH1A1PHLPP2SMN1; SMN2 | |
| SCHEMBL9629064 | 0.84 | GAA (0.84) | GAATDP1ALDH1A1PHLPP2KDM4E | |
| SCHEMBL6208445 | 0.84 | GAA (0.60) | GAATDP1ALDH1A1PHLPP2KDM4E | |
| SCHEMBL11358749 | 0.84 | GAA (0.68) | GAATDP1ALDH1A1PHLPP2KDM4E | |
| SCHEMBL13291921 | 0.83 | CNR2 (0.68) | TDP1ALDH1A1CNR2SMN1; SMN2MAPT | |
| SCHEMBL13291849 | 0.83 | TDP1 (0.66) | TDP1ALDH1A1KDM4ECNR2SMN1; SMN2 | |
| SCHEMBL13291922 | 0.83 | TDP1 (0.66) | TDP1ALDH1A1KDM4ECNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641729-B1 | USE OF FUNCTIONALIZED ONIUM SALTS AS A SOLUBLE SUPPORT FOR ORGANIC SYNTHESIS | CENTRE NAT RECH SCIENT (FR) | 2008-05-07 | — | — | EP | disclosed |