Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.60 |
| ▸ | ACHE | P22303 | 10/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055450 | 0.87 | TDP1 (0.73) | BCHEACHEGAATDP1ALDH1A1 | |
| SCHEMBL27579412 | 0.86 | TDP1 (0.71) | BCHEACHEGAATDP1ALDH1A1 | |
| SCHEMBL14218219 | 0.85 | GAA (0.62) | BCHEACHEGAATDP1ALDH1A1 | |
| SCHEMBL11287086 | 0.82 | GAA (0.71) | ACHEGAATDP1ALDH1A1PHLPP2 | |
| SCHEMBL29030409 | 0.81 | TDP1 (0.59) | TDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9629064 | 0.81 | GAA (0.84) | ACHEGAATDP1ALDH1A1PHLPP2 | |
| SCHEMBL7921543 | 0.81 | LMNA (0.66) | BCHEACHEALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7921547 | 0.81 | LMNA (0.66) | BCHEACHEALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11358749 | 0.80 | GAA (0.68) | ACHEGAATDP1ALDH1A1PHLPP2 | |
| SCHEMBL7915244 | 0.80 | LMNA (0.64) | BCHEACHEALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641729-B1 | USE OF FUNCTIONALIZED ONIUM SALTS AS A SOLUBLE SUPPORT FOR ORGANIC SYNTHESIS | CENTRE NAT RECH SCIENT (FR) | 2008-05-07 | — | — | EP | disclosed |