Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26495850 | 0.78 | MAPT (0.41) | MEN1KMT2AMAPTPRKD3EGFR | |
| SCHEMBL22828956 | 0.78 | TDP1 (0.40) | MEN1KMT2AMAPTPRKD3EGFR | |
| SCHEMBL25648742 | 0.77 | KMT2A (0.38) | MEN1KMT2AMAPTPRKD3EGFR | |
| SCHEMBL14185945 | 0.75 | EGFR (0.47) | MEN1KMT2AMAPTEGFRTDP1 | |
| SCHEMBL17487923 | 0.74 | PTGS1 (0.44) | MEN1KMT2AMAPTPRKD3EGFR | |
| SCHEMBL15332315 | 0.72 | ERN1 (0.43) | MEN1KMT2AMAPTPRKD3EGFR | |
| SCHEMBL2559807 | 0.70 | MEN1 (0.43) | MEN1KMT2AMAPTPRKD3EGFR | |
| SCHEMBL24283166 | 0.70 | MAPK10 (0.37) | MEN1KMT2AMAPTPRKD3EGFR | |
| SCHEMBL13890943 | 0.70 | MEN1 (0.40) | MEN1KMT2AMAPTPRKD3EGFR | |
| SCHEMBL28376321 | 0.69 | MAOA (0.46) | MEN1KMT2AMAPTPRKD3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057856-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1 AND/OR NF-KAPPAB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |