Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26495850 | 0.78 | MAPT (0.41) | MAPK10MAPTMEN1KMT2APRKD3 | |
| SCHEMBL20036833 | 0.75 | MAPT (0.41) | MAPK10MAPTMEN1KMT2APRKD3 | |
| SCHEMBL25794401 | 0.75 | KMT2A (0.36) | MAPTMEN1KMT2APRKD3EGFR | |
| SCHEMBL23904233 | 0.73 | MAPT (0.36) | MAPK10MAPTMEN1KMT2APRKD3 | |
| SCHEMBL25804586 | 0.72 | ACP1 (0.38) | MAPTMEN1KMT2APRKD3EGFR | |
| SCHEMBL22828956 | 0.72 | TDP1 (0.40) | MAPTMEN1KMT2APRKD3EGFR | |
| SCHEMBL17461539 | 0.72 | RAB9A (0.52) | MAPTMEN1KMT2ATDP1AURKA | |
| SCHEMBL26045155 | 0.72 | MAPT (0.36) | MAPK10MAPTMEN1KMT2APRKD3 | |
| SCHEMBL17461534 | 0.70 | PTGS1 (0.46) | MAPTMEN1KMT2APRKD3EGFR | |
| SCHEMBL14218238 | 0.70 | MEN1 (0.40) | MAPK10MAPTMEN1KMT2APRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728233-B1 | SUBSTITUTED PYRROLIDINE AMIDES II | GRUENENTHAL GMBH (DE) | 2022-04-20 | — | — | EP | disclosed |