Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493848 | 0.87 | KMT2A (0.55) | MAPTKMT2ANPSR1ALDH1A1MEN1 | |
| SCHEMBL3494013 | 0.86 | ALDH1A1 (0.54) | MAPTKMT2ANPSR1ALDH1A1MEN1 | |
| SCHEMBL13620529 | 0.80 | KMT2A (0.45) | MAPTRXFP1PPARGNCOA2KMT2A | |
| SCHEMBL13620316 | 0.79 | KMT2A (0.44) | MAPTRXFP1PPARGNCOA2KMT2A | |
| SCHEMBL3492879 | 0.77 | RXFP1 (0.61) | MAPTRXFP1PPARGNCOA2KMT2A | |
| SCHEMBL3491627 | 0.76 | KMT2A (0.48) | MAPTRXFP1PPARGNCOA2KMT2A | |
| SCHEMBL3491630 | 0.76 | KMT2A (0.49) | MAPTRXFP1PPARGNCOA2KMT2A | |
| SCHEMBL4521463 | 0.74 | KMT2A (0.58) | MAPTRXFP1PPARGNCOA2KMT2A | |
| SCHEMBL3491528 | 0.74 | KMT2A (0.54) | MAPTRXFP1PPARGNCOA2KMT2A | |
| SCHEMBL4515025 | 0.73 | KMT2A (0.57) | MAPTRXFP1PPARGNCOA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908765-A1 | THIENOPYRIMIDINE DERIVATIVE | ASKA Pharmaceutical Co., Ltd. (JP) | 2008-04-09 | — | — | EP | disclosed |