Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | THRA | P10827 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14218976 | 0.97 | THRB (0.42) | THRBMAPTTHRAKMT2AMEN1 | |
| SCHEMBL13283121 | 0.92 | THRB (0.46) | THRBMAPTKMT2ASMN1; SMN2GFER | |
| SCHEMBL14218989 | 0.90 | THRB (0.43) | THRBMAPTTHRAKMT2AMEN1 | |
| SCHEMBL11891430 | 0.88 | KMT2A (0.47) | THRBMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1945993 | 0.88 | THRB (0.42) | THRBMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13296350 | 0.86 | THRB (0.44) | THRBMAPTKMT2AALDH1A1 | |
| SCHEMBL18806545 | 0.83 | THRB (0.48) | THRBMAPTTHRAKMT2AMEN1 | |
| SCHEMBL2759475 | 0.83 | SMN1; SMN2 (0.43) | THRBMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL12806674 | 0.83 | THRB (0.39) | THRBMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL23581943 | 0.81 | MAPT (0.47) | THRBMAPTPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |