Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13283121 | 0.95 | THRB (0.46) | THRBKMT2AMAPTCCNCCDK8 | |
| SCHEMBL11891430 | 0.91 | KMT2A (0.47) | THRBKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL14218976 | 0.91 | THRB (0.42) | THRBKMT2AMAPTMEN1CCNC | |
| SCHEMBL3053163 | 0.89 | THRB (0.44) | THRBKMT2AMAPTMEN1RAB9A | |
| SCHEMBL14219065 | 0.88 | THRB (0.40) | THRBKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL18806545 | 0.86 | THRB (0.48) | THRBKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL2759475 | 0.85 | SMN1; SMN2 (0.43) | THRBKMT2AMAPTMEN1RAB9A | |
| SCHEMBL2398606 | 0.85 | KMT2A (0.50) | THRBKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL14218989 | 0.84 | THRB (0.43) | THRBKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL23581943 | 0.84 | MAPT (0.47) | THRBMAPTRAB9APKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110129622-A1 | ALIGNMENT LAYER FOR LCD | LACHEZAR KOMITOV (SE) | 2011-06-02 | — | — | US | disclosed |
| WO-2009156483-A1 | ALIGNMENT LAYER FOR LCD | KOMITOV LACHEZAR (SE) | 2009-12-30 | — | — | WO | disclosed |