Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858051 | 0.89 | MTNR1A (0.62) | MTNR1AMTNR1BLMNAL3MBTL1KMT2A | |
| SCHEMBL15242308 | 0.74 | MTNR1A (0.37) | MTNR1AMTNR1BLMNAKMT2AMEN1 | |
| SCHEMBL2867535 | 0.72 | MTNR1A (0.41) | MTNR1AMTNR1BLMNAKMT2AMEN1 | |
| SCHEMBL2858297 | 0.72 | MTNR1A (0.41) | MTNR1AMTNR1BKMT2AMEN1NPBWR1 | |
| SCHEMBL2853420 | 0.70 | ALDH1A1 (0.37) | MTNR1AMTNR1BLMNAL3MBTL1KMT2A | |
| SCHEMBL4393644 | 0.68 | MTNR1A (1.00) | MTNR1AMTNR1BALDH1A1NQO2KDM4E | |
| SCHEMBL7894816 | 0.68 | MTNR1A (0.80) | MTNR1AMTNR1BLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7086829 | 0.67 | NPSR1 (0.59) | MTNR1AMTNR1BLMNAL3MBTL1KMT2A | |
| SCHEMBL7894811 | 0.65 | MTNR1A (0.71) | MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL2674352 | 0.65 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911744-A1 | TRYPTOPHAN DERIVATIVE AND USE THEREOF | Somei, Masanori (JP) | 2008-04-16 | — | — | EP | disclosed |