SCHEMBL1421922

SCHEMBL1421922

CC(C)(C)OC(=O)N=C(N)n1cccn1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 9/20 0.45
ELANE P08246 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16945673 1.00 NOS1 (0.45) NOS1ELANE
SCHEMBL12446838 1.00 NOS1 (0.45) NOS1ELANE
SCHEMBL8208552 0.85 NOS1 (0.43) NOS1ELANE
SCHEMBL12062416 0.83 ELANE (0.36) NOS1ELANE
SCHEMBL12062418 0.83 ELANE (0.36) NOS1ELANE
SCHEMBL7827758 0.83 NOS1 (0.36) NOS1ELANE
SCHEMBL7827757 0.83 NOS1 (0.36) NOS1ELANE
SCHEMBL17560599 0.83 NOS1 (0.36) NOS1ELANE
SCHEMBL14936428 0.83 NOS1 (0.49) NOS1ELANE
SCHEMBL12447518 0.79 ELANE (0.33) NOS1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036560-A Radioactive medical isotope18F-labeled norepinephrine analogue as well as preparation method and application thereof 中国医学科学院阜外医院 2026-05-15 CN claimed
CN-122036560-A Radioactive medical isotope18F-labeled norepinephrine analogue as well as preparation method and application thereof 中国医学科学院阜外医院 2026-05-15 CN disclosed
US-12415828-B2 Modified oligonucleotides and methods for their synthesis NOOGEN LLC (RU) 2025-09-16 US disclosed
CN-114907301-B Ranitivir octanoate intermediate and preparation method thereof 上海医药工业研究院 2024-05-28 CN disclosed
US-11935803-B2 Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-03-19 US disclosed
CN-117396465-A Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same 阿斯克里斯有限公司 2024-01-12 CN disclosed
WO-2023199881-A1 METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE AND RESIST UNDERLAYER FILM FORMING COMPOSITION JSR株式会社 2023-10-19 WO disclosed
CN-111562720-B Photo-sensitized chemically amplified resist material, pattern forming method, semiconductor device, mask for lithography, and template for nanoimprint 东京毅力科创株式会社 2023-09-29 CN disclosed
CN-111116533-B Zanamivir and ranamivir intermediate and synthesis method thereof 中国科学院上海有机化学研究所 2022-11-22 CN disclosed
CN-114907301-A Ranitivir caprylate intermediate and preparation method thereof 上海医药工业研究院 2022-08-16 CN disclosed
WO-2004067521-A1 THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS ASTELLAS PHARMA INC. (JP) 2004-08-12 WO disclosed
EP-1442027-A1 SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2004-08-04 EP disclosed
CN-1419546-A 4, 5-dihydro-1H-pyrazole derivatives having CB 1-antagonistic activity SOLVAY PHARM BV (NL) 2003-05-21 CN disclosed
WO-2003031419-A1 SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2003-04-17 WO disclosed
US-6476060-B2 DRUG ABUSE; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS; CARDIOVASCUALR DISORDERS SOLVAY PHARMACEUTICALS, B.V. (NL) 2002-11-05 US disclosed
US-20010053788-A1 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity SOLVAY PHARMACEUTICALS B.V. 2001-12-20 US disclosed
EP-1037668-A1 TRANSFECTION PARTICLES Boehringer Ingelheim International GmbH (DE) 2000-09-27 EP disclosed
EP-0945138-A1 Transfection particles Université Louis Pasteur de Strasbourg (FR) 1999-09-29 EP disclosed
WO-1999029349-A1 TRANSFECTION PARTICLES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 1999-06-17 WO disclosed
EP-0743320-A2 Acyl guanidine and amidine prodrugs BRISTOL-MYERS SQUIBB COMPANY (US) 1996-11-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010053788-A1 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity CNR1, CNR2, CBR3 NOS1 3155/4885ELANE 3992/4885
US-12415828-B2 Modified oligonucleotides and methods for their synthesis RNGTT, TYMP, POLM NOS1 4361/4885ELANE 2895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.