Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730569 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL22677485 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL10305534 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL14543527 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL18474342 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL14098332 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL22418213 | 0.81 | CA12 (0.35) | EPHX1CA12CA9KDM4EALDH1A1 | |
| SCHEMBL6436067 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL23506579 | 0.79 | NPC1 (0.67) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 | |
| SCHEMBL585161 | 0.79 | NPC1 (0.67) | SMN1; SMN2NPC1RAB9AMAPTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1573373-B1 | OPTICAL COMPENSATING SHEET, PRODUCTION METHOD THEREOF, OPTICAL FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | FUJIFILM CORP (JP) | 2008-04-16 | — | — | EP | disclosed |