Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31695396 | 1.00 | CSNK2A1 (0.61) | CSNK2A1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL9380353 | 0.98 | CSNK2A1 (0.59) | CSNK2A1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL11341497 | 0.83 | CSNK2A1 (0.45) | CSNK2A1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL9741686 | 0.83 | CSNK2A1 (0.55) | CSNK2A1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL8123981 | 0.81 | CSNK2A1 (0.44) | CSNK2A1MEN1KMT2AGFERPPARG | |
| SCHEMBL4174657 | 0.81 | PARP1 (0.44) | CSNK2A1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL31627797 | 0.79 | CSNK2A1 (0.68) | CSNK2A1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL467550 | 0.79 | CSNK2A1 (0.68) | CSNK2A1MEN1KMT2AGFERALDH1A1 | |
| Potassium Ion SCHEMBL9380348 | 0.79 | CSNK2A1 (0.42) | CSNK2A1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL31506855 | 0.78 | CYP46A1 (0.53) | CSNK2A1ALDH1A1KDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241385-B | Beta-acyloxy enamide derivative and preparation method and application thereof | 江西师范大学 | 2025-03-25 | — | — | CN | claimed |
| CN-119241385-A | Beta-acyloxy enamide derivative and preparation method and application thereof | 江西师范大学 | 2025-01-03 | — | — | CN | claimed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-116396159-A | Synthesis method of 2,2' -biphenyl dicarboxylic acid compound | 湖南大学 | 2023-07-07 | — | — | CN | claimed |
| CN-109810067-B | Preparation method of suvorexant intermediate | 扬子江药业集团有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-109810067-A | A kind of preparation method of Su Woleisheng intermediate | 扬子江药业集团有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-103224482-A | Isocoumarin compound, derivatives and synthesis method thereof | UNIV SHANGHAI JIAOTONG | 2013-07-31 | — | — | CN | claimed |
| EP-2297135-A1 | PROCESS FOR THE PREPARATION OF AN OREXIN RECEPTOR ANTAGONIST | Merck Sharp & Dohme Corp. (US) | 2011-03-23 | — | — | EP | claimed |
| WO-2009143033-A1 | PROCESS FOR THE PREPARATION OF AN OREXIN RECEPTOR ANTAGONIST | MERCK & CO., INC. (US) | 2009-11-26 | — | — | WO | claimed |
| EP-3856179-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-13 | — | — | EP | disclosed |
| EP-4635949-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTYL[C]PYRROLE DERIVATIVE, PREPARATION METHOD, INTERMEDIATE AND USE THEREOF | Jiangsu NHWA Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-05 | — | — | US | disclosed |
| CN-120081802-A | Heterocyclic substituted benzamide derivative and application thereof | 南华大学附属第一医院 | 2025-06-03 | — | — | CN | disclosed |
| CN-116217593-B | Octahydropyrrolo [3,4-c ] pyrrole methyl ketone derivative and application thereof | 江苏恩华药业股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| US-4006145-A | CNS DEPRESSANTS, NEUROLEPTICS | HOFFMANN-LA ROCHE INC. (US) | 1977-02-01 | — | — | US | disclosed |
| US-4006144-A | CNS DEPRESSANTS, NEUROLEPTICS | HOFFMANN-LA ROCHE INC. (US) | 1977-02-01 | — | — | US | disclosed |
| US-3996229-A | DEPRESSANTS, NEUROLEPTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3966737-A | NEUROLEPTIC | HOFFMANN-LA ROCHE INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3954764-A | NEUROLEPTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3954769-A | NEUROLEPTIC AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | CSNK2A1 4197/4885MEN1 3413/4885KMT2A 1722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.