Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220022 | 1.00 | EPHX1 (0.43) | EPHX1POLBESR1ESR2CYP3A4 | |
| SCHEMBL14219983 | 0.90 | POLB (0.41) | EPHX1POLB | |
| SCHEMBL14219588 | 0.90 | POLB (0.41) | EPHX1POLB | |
| SCHEMBL14219935 | 0.90 | POLB (0.41) | EPHX1POLB | |
| SCHEMBL14219321 | 0.86 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL14219401 | 0.86 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL14219459 | 0.86 | PDPK1 (0.38) | ESR1ESR2 | |
| SCHEMBL14220027 | 0.85 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL14219406 | 0.84 | ESR1 (0.41) | ESR1ESR2 | |
| SCHEMBL14219392 | 0.84 | ESR1 (0.35) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |