Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.51 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.51 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.51 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.51 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.51 |
| ▸ | MPL | P40238 | 9/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | ATIC | P31939 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30218697 | 0.85 | SENP2 (0.44) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL18936300 | 0.85 | SENP2 (0.44) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL2624859 | 0.83 | MPL (0.57) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL13460242 | 0.83 | LMNA (0.55) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL18078576 | 0.81 | SENP2 (0.64) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL18937495 | 0.81 | SENP2 (0.56) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL28657871 | 0.79 | TTR (0.55) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL2662857 | 0.76 | CYP1A2 (0.54) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL437289 | 0.74 | CYP2D6 (0.51) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL29409575 | 0.74 | TTR (0.61) | SENP2SENP1SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911451-A1 | Protein-kinase CK2 inhibitors and their therapeutic applications | INSERM (Institut National de la Santé et de la Recherche Medicale) (FR) | 2008-04-16 | — | — | EP | disclosed |