Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 20/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219646 | 0.89 | MEN1 (0.39) | MAP2K1MAP2K2ABCB11NQO2 | |
| SCHEMBL14223214 | 0.86 | MEN1 (0.55) | MAP2K1MAP2K2 | |
| SCHEMBL14220176 | 0.85 | MAP2K1 (0.47) | MAP2K1MAP2K2ABCB11NQO2 | |
| SCHEMBL14220111 | 0.81 | ALDH1A1 (0.40) | MAP2K1 | |
| SCHEMBL14220113 | 0.80 | MAP2K1 (0.49) | MAP2K1MAP2K2ABCB11NQO2 | |
| SCHEMBL14220160 | 0.80 | MAP2K1 (0.49) | MAP2K1MAP2K2ABCB11NQO2 | |
| SCHEMBL14219652 | 0.80 | MAP2K1 (0.43) | MAP2K1MAP2K2ABCB11NQO2 | |
| SCHEMBL14219661 | 0.80 | MAP2K1 (0.33) | MAP2K1MAP2K2 | |
| SCHEMBL14219856 | 0.80 | MAP2K1 (0.39) | MAP2K1MAP2K2ABCB11NQO2 | |
| SCHEMBL14222856 | 0.79 | MEN1 (0.40) | MAP2K1MAP2K2ABCB11NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |