Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.33 |
| ▸ | SMC2 | O95347 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.33 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219646 | 0.91 | MEN1 (0.39) | MAP2K1MAP2K2DHODHMEN1KMT2A | |
| SCHEMBL14219856 | 0.89 | MAP2K1 (0.39) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL14219726 | 0.86 | MAP2K1 (0.34) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL14220130 | 0.81 | ALDH1A1 (0.37) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL14219658 | 0.80 | MAP2K1 (0.39) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL14219727 | 0.80 | MEN1 (0.34) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL14219614 | 0.80 | MAP2K1 (0.42) | MAP2K1MAP2K2 | |
| SCHEMBL14223049 | 0.80 | MAP2K1 (0.37) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL14219716 | 0.80 | ALDH1A1 (0.36) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL14220111 | 0.80 | ALDH1A1 (0.40) | MAP2K1DHODHMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |