Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219454 | 1.00 | SPHK1 (0.37) | SPHK1SIGMAR1SPHK2POLBCCR1 | |
| SCHEMBL14219933 | 0.91 | MAOB (0.35) | SIGMAR1POLB | |
| SCHEMBL14219963 | 0.91 | MAOB (0.35) | SIGMAR1POLB | |
| SCHEMBL14219383 | 0.91 | SPHK1 (0.34) | SPHK1SIGMAR1SPHK2POLB | |
| SCHEMBL14219970 | 0.89 | MAOA (0.34) | SPHK1 | |
| SCHEMBL14219577 | 0.89 | MAOA (0.34) | SPHK1 | |
| SCHEMBL14219462 | 0.87 | CCR1 (0.39) | POLBCCR1 | |
| SCHEMBL14219922 | 0.86 | CYP2D6 (0.32) | POLBCCR1 | |
| SCHEMBL14219393 | 0.86 | CYP2D6 (0.32) | POLBCCR1 | |
| SCHEMBL14220025 | 0.84 | ADRB2 (0.39) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |