SCHEMBL14219913

SCHEMBL14219913

C[C@H](Cc1ccc(C2CCC(c3ccc(C#N)c(F)c3)CC2)cc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSC P53634 7/20 0.35
TRPV4 Q9HBA0 1/20 0.35
CTSK P43235 1/20 0.34
EP300 Q09472 5/20 0.34
CYP11B1 P15538 3/20 0.33
CYP11B2 P19099 3/20 0.33
ENPP2 Q13822 1/20 0.33
KDM1A O60341 1/20 0.33
CYP2D6 P10635 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
NOS2 P35228 1/20 0.33
HAT1 O14929 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14219972 0.91 AOC3 (0.37) CTSCCTSKEP300ENPP2HAT1
SCHEMBL14219967 0.89 AOC3 (0.37) CTSCCTSKEP300ENPP2
SCHEMBL14219928 0.89 AOC3 (0.37) CTSCCTSKEP300ENPP2
SCHEMBL14219461 0.87 CXCR2 (0.36) TRPV4CTSKEP300
SCHEMBL14219459 0.86 PDPK1 (0.38) KDM1A
SCHEMBL14219321 0.83 ESR1 (0.36)
SCHEMBL14219401 0.83 ESR1 (0.36)
SCHEMBL14219468 0.82 PPARG (0.38) SLC6A2SLC6A4
SCHEMBL14220026 0.82 PPARG (0.38) SLC6A2SLC6A4
SCHEMBL14219492 0.82 KDM4E (0.36) TRPV4EP300CYP11B1CYP11B2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1650285-B1 Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element SEIMI CHEM KK (JP) 2008-04-30 EP disclosed