Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 5/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219598 | 0.89 | EP300 (0.33) | CXCR2GRM2EP300CNR1CNR2 | |
| SCHEMBL14219931 | 0.88 | GRM2 (0.33) | CXCR2GRM2EP300CNR1CNR2 | |
| SCHEMBL14219961 | 0.88 | GRM2 (0.33) | CXCR2GRM2EP300CNR1CNR2 | |
| SCHEMBL14219913 | 0.87 | CTSC (0.35) | EP300TRPV4CTSK | |
| SCHEMBL14219321 | 0.87 | ESR1 (0.36) | IDO1ESR1ESR2 | |
| SCHEMBL14219401 | 0.87 | ESR1 (0.36) | IDO1ESR1ESR2 | |
| SCHEMBL14220027 | 0.85 | ESR1 (0.36) | IDO1ESR1ESR2 | |
| SCHEMBL14219406 | 0.84 | ESR1 (0.41) | IDO1ESR1ESR2 | |
| SCHEMBL14219392 | 0.84 | ESR1 (0.35) | IDO1MEN1KMT2AESR1ESR2 | |
| SCHEMBL14219459 | 0.84 | PDPK1 (0.38) | ESR1ESR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |