SCHEMBL14219988

SCHEMBL14219988

C[C@H](Cc1ccc(CCC2CCC(c3ccc(F)c(F)c3)CC2)cc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.34
HCRTR2 O43614 1/20 0.34
PDPK1 O15530 1/20 0.34
SIGMAR1 Q99720 1/20 0.33
POLB P06746 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14219926 0.93 HCRTR1 (0.38) HCRTR1HCRTR2PDPK1SIGMAR1
SCHEMBL14219956 0.93 HCRTR1 (0.38) HCRTR1HCRTR2PDPK1SIGMAR1
SCHEMBL14219990 0.90 PPARG (0.33) POLBMAOB
SCHEMBL14219596 0.90 PPARG (0.33) POLBMAOB
SCHEMBL14219459 0.90 PDPK1 (0.38) PDPK1
SCHEMBL14219992 0.89 RORC (0.33) MAOB
SCHEMBL14219581 0.89 RORC (0.33) MAOB
SCHEMBL14219479 0.88 MAOB (0.34) HCRTR1HCRTR2SIGMAR1POLBMAOB
SCHEMBL14219964 0.88 MAOB (0.34) HCRTR1HCRTR2SIGMAR1POLBMAOB
SCHEMBL14219972 0.88 AOC3 (0.37) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1650285-B1 Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element SEIMI CHEM KK (JP) 2008-04-30 EP disclosed