Benproperine

Benproperine

SCHEMBL142207

CC(COc1ccccc1Cc1ccccc1)N1CCCCC1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 10/20 0.58
DRD1 P21728 7/20 0.58
DRD5 P21918 6/20 0.58
DRD4 P21917 5/20 0.58
DRD3 P35462 5/20 0.58
DRD2 P14416 5/20 0.58
HTR1A P08908 1/20 0.45
ADRA1D P25100 1/20 0.45
ADRA1A P35348 1/20 0.45
ADRA1B P35368 1/20 0.45
TP53 P04637 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
TSHR P16473 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HPGD P15428 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benproperine SCHEMBL17660555 1.00 HRH1 (0.58) HRH1DRD1DRD5DRD4DRD3
Benproperine SCHEMBL29619460 1.00 HRH1 (0.58) HRH1DRD1DRD5DRD4DRD3
Benproperine SCHEMBL28016122 1.00 HRH1 (0.58) HRH1DRD1DRD5DRD4DRD3
Benproperine SCHEMBL17660552 1.00 HRH1 (0.58) HRH1DRD1DRD5DRD4DRD3
Benproperine SCHEMBL15251665 0.99 HRH1 (0.56) HRH1DRD1DRD5DRD4DRD3
Benproperine SCHEMBL15251659 0.99 HRH1 (0.56) HRH1DRD1DRD5DRD4DRD3
Benproperine SCHEMBL28399849 0.99 HRH1 (0.56) HRH1DRD1DRD5DRD4DRD3
Benproperine SCHEMBL15251668 0.99 HRH1 (0.56) HRH1DRD1DRD5DRD4DRD3
Benproperine SCHEMBL31351271 0.93 HRH1 (0.51) HRH1DRD1DRD5DRD4DRD3
Benproperine SCHEMBL348563 0.93 HRH1 (0.51) HRH1DRD1DRD5DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1048 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 US claimed
EP-4510999-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS Bristol-Myers Squibb Company (US) 2025-02-26 EP claimed
CN-119258134-A Application of traditional Chinese medicine composition in preparation of medicine for preventing and treating cough variant asthma 江苏康缘药业股份有限公司 2025-01-07 CN claimed
CN-119212681-A Method for preparing 3-D printed pharmaceutical products 百时美施贵宝公司 2024-12-27 CN claimed
US-20240226084-A9 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS TECHFIELDS PHARMA CO., LTD. (CN) 2024-07-11 US claimed
CN-112166106-B Cancer metastasis inhibitors by inhibiting cancer cell migration and invasion VS药物技术公司 2024-05-24 CN claimed
US-20240165020-A1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-05-23 US claimed
EP-4360653-A2 LIQUISOFT CAPSULES Patheon Softgels Inc. (US) 2024-05-01 EP claimed
US-20240131017-A1 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS TECHFIELDS PHARMA CO., LTD. (CN) 2024-04-25 US claimed
US-20030206942-A1 Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent MCNEIL-PPC, INC 2003-11-06 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
CN-1421217-A Cough-relieving medicine TANG YI (CN) 2003-06-04 CN claimed
CN-1329890-A Dual-layer slow releasing tablet of benproperine phosphate HUANG ZHENHUA (CN) 2002-01-09 CN claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
CN-1176137-A Cane sugar-free notoginseng flower essence and its preparation YUNNAN BAIYAO GROUP CORP LTD (CN) 1998-03-18 CN claimed
EP-0580860-B1 METHOD OF MANUFACTURING SOLID DISPERSION NIPPON SHINYAKU CO LTD (JP) 1997-10-22 EP claimed
CN-1104500-A Composite benproperine BAIYUNSHAN PHARMACEUTICS STOCK (CN) 1995-07-05 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226084-A9 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS HRH4, HCAR2, PAH HRH1 7/4885DRD1 4330/4885DRD5 3549/4885
US-20240131017-A1 HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS HRH4, HCAR2, PAH HRH1 7/4885DRD1 4330/4885DRD5 3549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.