Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 10/20 | 0.58 |
| ▸ | DRD1 | P21728 | 7/20 | 0.58 |
| ▸ | DRD5 | P21918 | 6/20 | 0.58 |
| ▸ | DRD4 | P21917 | 5/20 | 0.58 |
| ▸ | DRD3 | P35462 | 5/20 | 0.58 |
| ▸ | DRD2 | P14416 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benproperine SCHEMBL142207 | 1.00 | HRH1 (0.58) | HRH1DRD1DRD5DRD4DRD3 | |
| Benproperine SCHEMBL17660555 | 1.00 | HRH1 (0.58) | HRH1DRD1DRD5DRD4DRD3 | |
| Benproperine SCHEMBL29619460 | 1.00 | HRH1 (0.58) | HRH1DRD1DRD5DRD4DRD3 | |
| Benproperine SCHEMBL17660552 | 1.00 | HRH1 (0.58) | HRH1DRD1DRD5DRD4DRD3 | |
| Benproperine SCHEMBL15251665 | 0.99 | HRH1 (0.56) | HRH1DRD1DRD5DRD4DRD3 | |
| Benproperine SCHEMBL15251659 | 0.99 | HRH1 (0.56) | HRH1DRD1DRD5DRD4DRD3 | |
| Benproperine SCHEMBL28399849 | 0.99 | HRH1 (0.56) | HRH1DRD1DRD5DRD4DRD3 | |
| Benproperine SCHEMBL15251668 | 0.99 | HRH1 (0.56) | HRH1DRD1DRD5DRD4DRD3 | |
| Benproperine SCHEMBL31351271 | 0.93 | HRH1 (0.51) | HRH1DRD1DRD5DRD4DRD3 | |
| Benproperine SCHEMBL348563 | 0.93 | HRH1 (0.51) | HRH1DRD1DRD5DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540504-A | High penetration prodrug compositions and pharmaceutical compositions for treating pulmonary diseases | TECHFIELDS PHARMA CO LTD | 2015-04-22 | — | — | CN | claimed |