SCHEMBL1422115

SCHEMBL1422115

O=C(F)C1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9132306 1.00 CES2 (0.35)
SCHEMBL12212961 0.90 CHRNB2 (0.32)
SCHEMBL9437082 0.86
SCHEMBL12806512 0.86
SCHEMBL14337058 0.85 EPHX1 (0.37)
SCHEMBL2189503 0.83
SCHEMBL14274417 0.79 EPHX1 (0.33)
SCHEMBL12213051 0.78 CHRNB2 (0.39)
SCHEMBL14444670 0.75 ESR2 (0.31)
SCHEMBL7532313 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2488510-B1 Amides and thioamides as pest control agents BAYER IP GMBH (DE) 2017-03-29 EP claimed
EP-2725022-B1 New amides as pest control agents BAYER CROPSCIENCE AG (DE) 2017-03-29 EP claimed
EP-2297130-B1 NEW HETEROAROMATIC AMIDES AND THIOAMIDES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2014-09-17 EP claimed
US-8536204-B2 Amides and thioamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US claimed
EP-3532473-B1 HETEROBICYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES BRISTOL MYERS SQUIBB CO (US) 2021-09-29 EP disclosed
EP-2488510-B1 Amides and thioamides as pest control agents BAYER IP GMBH (DE) 2017-03-29 EP disclosed
EP-2725022-B1 New amides as pest control agents BAYER CROPSCIENCE AG (DE) 2017-03-29 EP disclosed
EP-2730569-B1 New amides and thioamides as pest control agents BAYER CROPSCIENCE AG (DE) 2016-11-30 EP disclosed
US-20160316755-A1 Novel Heteroaromatic Amides and Thioamides as Pesticides BAYER CROPSCIENCE AG (DE) 2016-11-03 US disclosed
US-9428487-B2 Heteroaromatic amides and thioamides as pesticides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-08-30 US disclosed
EP-2297130-B1 NEW HETEROAROMATIC AMIDES AND THIOAMIDES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2014-09-17 EP disclosed
EP-2730569-A1 New amides and thioamides as pest control agents Bayer CropScience AG (DE) 2014-05-14 EP disclosed
US-20030028029-A1 Process for production of piperidine derivatives BARCLAYS BANK PLC, AS THE COLLATERAL AGENT 2003-02-06 US disclosed
US-6458958-B1 PROCESS OF PREPARING A PIPERIDINE DERIVATIVE COMPOUND OF THE FORMULA: ACYLATING AN .ALPHA.,.ALPHA.-DISUBSTITUTED-METHYLBENZENE DERIVATIVE HAVING THE FORMULA: ALBANY MOLECULAR RESEARCH, INC. 2002-10-01 US disclosed
US-6444824-B1 ANTISEROTONINE AGENTS; SIDE EFFECT REDUCTION ALBANY MOLECULAR RESEARCH, INC. 2002-09-03 US disclosed
US-6153754-A Process for production of piperidine derivatives ALBANY MOLECULAR RESEARCH, INC. (US) 2000-11-28 US disclosed
EP-0868182-A4 PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES ALBANY MOLECULAR RES INC (US) 1999-04-07 EP disclosed
EP-0868182-A1 PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES ALBANY MOLECULAR RESEARCH, INC. (US) 1998-10-07 EP disclosed
WO-1997023213-A1 PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES ALBANY MOLECULAR RESEARCH, INC. (US) 1997-07-03 WO disclosed
US-4555370-A CYANTATION OF ACYL. FLUORIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-26 US disclosed