Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 3/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.32 |
| ▸ | FGF1 | P05230 | 3/20 | 0.32 |
| ▸ | FGF2 | P09038 | 3/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | SERPINC1 | P01008 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381063 | 0.82 | PTPN1 (0.48) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12777936 | 0.77 | GJB2 (0.42) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL14846435 | 0.77 | GJB2 (0.42) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL16160499 | 0.76 | SSTR1 (0.50) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL14846437 | 0.76 | GJB2 (0.45) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL13381060 | 0.75 | PTPN1 (0.47) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL19277305 | 0.74 | SSTR1 (0.42) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL16770611 | 0.74 | SSTR1 (0.54) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL19356278 | 0.74 | SSTR1 (0.54) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL13605427 | 0.74 | SSTR1 (0.54) | GJB2SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008041131-A2 | ANTICOAGULANT COMPOUNDS | ENDOTIS PHARMA (FR) | 2008-04-10 | — | — | WO | disclosed |