Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.36 |
| ▸ | RELA | Q04206 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18414121 | 0.89 | GAA (0.42) | GAANFKB1NFKB2RELAKMT2A | |
| SCHEMBL7910651 | 0.80 | GAA (0.43) | GAANFKB1NFKB2RELAKMT2A | |
| SCHEMBL7910653 | 0.80 | GAA (0.43) | GAANFKB1NFKB2RELAKMT2A | |
| SCHEMBL7096995 | 0.79 | GAA (0.42) | GAANFKB1NFKB2RELAKMT2A | |
| SCHEMBL7096998 | 0.79 | GAA (0.42) | GAANFKB1NFKB2RELAKMT2A | |
| SCHEMBL7902401 | 0.79 | ALDH1A1 (0.40) | GAANFKB1NFKB2RELAKMT2A | |
| SCHEMBL7902399 | 0.79 | ALDH1A1 (0.40) | GAANFKB1NFKB2RELAKMT2A | |
| SCHEMBL7455128 | 0.75 | KMT2A (0.55) | GAANFKB1NFKB2RELAKMT2A | |
| SCHEMBL7676585 | 0.73 | PIK3CD (0.35) | GAANFKB1NFKB2RELA | |
| SCHEMBL17236211 | 0.72 | GAA (0.39) | GAANFKB1NFKB2RELAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008046232-A1 | AZIRIDINE ALDEHYDES, AZIRIDINE-CONJUGATED AMINO DERIVATIVES, AZIRIDINE-CONJUGATED BIOMOLECULES AND PROCESSES FOR THEIR PREPARATION | YUDIN ANDREI K (CA) | 2008-04-24 | — | — | WO | disclosed |