Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14172845 | 0.89 | ACHE (0.51) | ACHEKDM2BCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL14172846 | 0.79 | CYP11B1 (0.47) | NPY5RCYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL14172825 | 0.77 | CYP11B1 (0.43) | NPY5RCYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL14223000 | 0.77 | NPY5R (0.38) | NPY5RCYP11B1CYP11B2CYP3A4LMNA | |
| SCHEMBL14172847 | 0.74 | CYP3A4 (0.41) | NPY5RCYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL14172826 | 0.73 | CHRNB2 (0.48) | CYP11B1CYP11B2CYP19A1CYP3A4LMNA | |
| SCHEMBL14172610 | 0.72 | CYP2C9 (0.43) | CYP11B2MAPTSMN1; SMN2CYP2C9NPC1 | |
| SCHEMBL14172607 | 0.70 | NPY5R (0.37) | NPY5RCYP11B1CYP11B2CYP3A4LMNA | |
| SCHEMBL14172611 | 0.70 | STIM1 (0.41) | NPY5RCYP11B1CYP11B2CYP3A4MAPT | |
| SCHEMBL14172608 | 0.69 | NPC1 (0.48) | CYP11B1CYP11B2LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039520-A2 | FUSED RING COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2008-04-03 | — | — | WO | disclosed |