Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26343486 | 0.79 | CNR1 (0.40) | CA2CA1ZDHHC7CTSKMAPK1 | |
| SCHEMBL29186321 | 0.77 | ZDHHC7 (0.41) | CA2ZDHHC7CNR1 | |
| SCHEMBL18949076 | 0.73 | CA2 (0.42) | CA2CA1MAPK1 | |
| SCHEMBL30476795 | 0.72 | CHRM1 (0.45) | CA2CA1MAPK1 | |
| SCHEMBL12966169 | 0.72 | HDAC7 (0.36) | CA2CA1ZDHHC7ALDH1A1 | |
| SCHEMBL936329 | 0.72 | CA2 (0.44) | CA2ZDHHC7CNR1 | |
| SCHEMBL936709 | 0.72 | CA2 (0.44) | CA2ZDHHC7CNR1 | |
| SCHEMBL9929004 | 0.69 | GPR84 (0.44) | CA2ZDHHC7CNR1 | |
| SCHEMBL1257559 | 0.69 | GPR84 (0.44) | CA2ZDHHC7CNR1 | |
| SCHEMBL1258612 | 0.69 | GPR84 (0.44) | CA2ZDHHC7CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008041090-A1 | MALANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONIST PYRIDINONES | PFIZER LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |