Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729550 | 0.76 | NPC1 (0.38) | NPSR1KDM4EMAPTKMT2ANPC1 | |
| SCHEMBL1350185 | 0.74 | ABL1 (0.64) | KDM4EMAPTKMT2ACYP11B2SMN1; SMN2 | |
| SCHEMBL10265083 | 0.73 | ALDH1A1 (0.58) | KDM4EMAPTLMNARAF1MAPK14 | |
| SCHEMBL10264701 | 0.73 | RAF1 (0.65) | NPSR1KDM4ERAF1MAPK14RXFP1 | |
| SCHEMBL14223408 | 0.72 | KMT2A (0.68) | NPSR1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL24131808 | 0.71 | HPGD (0.42) | NPSR1KDM4EMAPTLMNARAF1 | |
| SCHEMBL4147003 | 0.71 | HPGD (0.42) | KDM4EMAPTLMNARAF1MAPK14 | |
| SCHEMBL2158389 | 0.71 | KDM4E (0.73) | NPSR1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL13715768 | 0.71 | KDM4E (0.74) | NPSR1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL20894133 | 0.71 | MAPT (0.42) | KDM4EMAPTKMT2ALMNAMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | disclosed |