Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13823413 | 0.73 | POLB (0.31) | POLBMAPT | |
| SCHEMBL21243947 | 0.72 | PTPN1 (0.31) | POLBMAPTKMT2AALDH1A1 | |
| SCHEMBL31006809 | 0.71 | OPRK1 (0.36) | POLBMAPTKMT2AALDH1A1 | |
| SCHEMBL2377502 | 0.70 | CA1 (0.39) | CA1CA2CA4KMT2A | |
| SCHEMBL959131 | 0.70 | MAPT (0.43) | POLBMAPTCA1CA2CA4 | |
| SCHEMBL17459557 | 0.68 | CA1 (0.32) | CA1CA2CA4KMT2AALDH1A1 | |
| SCHEMBL1187321 | 0.68 | CA1 (0.34) | CA1CA2CA4KMT2A | |
| SCHEMBL9971744 | 0.68 | CA1 (0.34) | CA1CA2CA4KMT2A | |
| SCHEMBL22715962 | 0.67 | — | — | |
| SCHEMBL6294540 | 0.66 | GPR119 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351720-B2 | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-01 | — | — | US | disclosed |