Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.51 |
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14224125 | 0.85 | SMN1; SMN2 (0.55) | — | |
| SCHEMBL14223781 | 0.84 | MTNR1A (0.53) | MTNR1AMTNR1BF9F10PLAU | |
| SCHEMBL14224122 | 0.81 | NPC1 (0.61) | L3MBTL1 | |
| SCHEMBL5127848 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1BF9F10PLAU | |
| SCHEMBL1520603 | 0.80 | MTNR1A (0.54) | MTNR1AMTNR1BF9F10PLAU | |
| SCHEMBL9340269 | 0.80 | MTNR1A (0.54) | MTNR1AMTNR1BF9F10PLAU | |
| SCHEMBL8330083 | 0.80 | MTNR1A (0.54) | MTNR1AMTNR1BF9F10PLAU | |
| SCHEMBL14224028 | 0.78 | MAPT (0.49) | L3MBTL1 | |
| SCHEMBL8384291 | 0.75 | MTNR1A (0.60) | MTNR1AMTNR1BAPAF1 | |
| SCHEMBL8384245 | 0.75 | MTNR1A (0.60) | MTNR1AMTNR1BAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355037-B2 | Thermolabile hydroxyl protecting groups and methods of use | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-04-08 | — | — | US | disclosed |