Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.49 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14224125 | 0.89 | SMN1; SMN2 (0.55) | LMNAKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL14224123 | 0.88 | MAPT (0.48) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL14224121 | 0.78 | MTNR1A (0.51) | L3MBTL1 | |
| SCHEMBL14224026 | 0.75 | SMN1; SMN2 (0.58) | LMNAKMT2ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL5947688 | 0.73 | EPHX2 (0.72) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL18941694 | 0.71 | ALDH1A1 (0.48) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL12376683 | 0.70 | ALDH1A1 (0.69) | MAPTLMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL6402844 | 0.69 | HDAC1 (0.50) | MAPTALDH1A1KMT2ATP53RAB9A | |
| SCHEMBL27712528 | 0.69 | SMN1; SMN2 (0.61) | MAPTLMNAALDH1A1KMT2ATP53 | |
| SCHEMBL8759694 | 0.69 | KMT2A (0.55) | MAPTLMNAALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355037-B2 | Thermolabile hydroxyl protecting groups and methods of use | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-04-08 | — | — | US | disclosed |