Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 7/20 | 0.42 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912147 | 0.93 | HDAC1 (0.41) | TERTHDAC1CYP3A4CYP2C19RORC | |
| SCHEMBL1109252 | 0.87 | HDAC1 (0.47) | TERTHDAC1CYP3A4NR1H4HDAC3 | |
| SCHEMBL14196121 | 0.82 | NPC1 (0.38) | SMN1; SMN2 | |
| SCHEMBL404400 | 0.82 | RARB (0.42) | HDAC1CYP3A4CYP2C19HDAC3HDAC8 | |
| SCHEMBL1912280 | 0.82 | ANPEP (0.46) | MAPT | |
| SCHEMBL1912240 | 0.81 | HDAC1 (0.48) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13825444 | 0.80 | TERT (0.42) | TERTCYP3A4CYP2C19RORC | |
| SCHEMBL403750 | 0.80 | NPC1 (0.44) | SMN1; SMN2 | |
| SCHEMBL10286728 | 0.79 | ALDH1A1 (0.60) | HDAC1CYP3A4CYP2C19HDAC3HDAC8 | |
| SCHEMBL402320 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |