Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14224778 | 0.86 | TSHR (0.43) | CA12CA1CA2CA3CA4 | |
| SCHEMBL14197096 | 0.85 | GAA (0.39) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL14224657 | 0.83 | FNTA (0.44) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL14224777 | 0.83 | GAA (0.49) | ALDH1A1ACACBNFKB1SMN1; SMN2GAA | |
| SCHEMBL14197101 | 0.82 | FNTA (0.48) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL18251699 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPC1RAB9AP2RX7 | |
| SCHEMBL14197187 | 0.72 | TSHR (0.42) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7356728 | 0.72 | CA12 (0.72) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL14197089 | 0.69 | GAA (0.48) | ALDH1A1ACACBSMN1; SMN2GAA | |
| SCHEMBL14224512 | 0.69 | KMT2A (0.49) | ALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354919-B2 | Isoxazole compositions useful as inhibitors of ERK | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-04-08 | — | — | US | disclosed |