Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28410400 | 0.87 | CYP11B1 (0.47) | CYP11B1CYP11B2PIP5K1CHSD17B10KDM4E | |
| SCHEMBL29642567 | 0.79 | HSD17B10 (0.40) | CYP11B1CYP11B2HSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL24119655 | 0.79 | HSD17B10 (0.40) | CYP11B1CYP11B2HSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL18107164 | 0.74 | CYP11B1 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL16847686 | 0.74 | CYP11B1 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL28678330 | 0.72 | GSK3B (0.41) | PIP5K1CKDM4ERAB9ASMN1; SMN2MAPK8 | |
| SCHEMBL17156153 | 0.70 | CYP11B1 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL17156152 | 0.70 | CYP11B1 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL23597417 | 0.68 | CYP11B1 (0.35) | CYP11B1CYP11B2HSD17B10KDM4ERAB9A | |
| SCHEMBL23581411 | 0.68 | CYP11B1 (0.35) | CYP11B1CYP11B2HSD17B10KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698395-B | Transforming growth factor receptor antagonist, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-113698395-A | Transforming growth factor receptor antagonist, preparation method and application thereof | 成都倍特药业股份有限公司 | 2021-11-26 | — | — | CN | disclosed |