Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 5/20 | 0.56 |
| ▸ | PRKCB | P05771 | 5/20 | 0.56 |
| ▸ | PRKCA | P17252 | 5/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.56 |
| ▸ | PRKCH | P24723 | 4/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.56 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.56 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.56 |
| ▸ | CAMK2B | Q13554 | 3/20 | 0.56 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.56 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.56 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.56 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.56 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.56 |
| ▸ | STK16 | O75716 | 1/20 | 0.56 |
| ▸ | PAK3 | O75914 | 1/20 | 0.56 |
| ▸ | CDK14 | O94921 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | KIT | P10721 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13915330 | 0.76 | PRKCG (0.55) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| SCHEMBL588318 | 0.76 | PRKCG (0.55) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| SCHEMBL28297895 | 0.74 | PRKCG (0.64) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| SCHEMBL30445335 | 0.74 | PRKCG (0.51) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Hydrochloric Acid SCHEMBL29784988 | 0.74 | PRKCG (0.77) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Hydrochloric Acid SCHEMBL27993565 | 0.73 | PRKCG (0.65) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| SCHEMBL14555078 | 0.72 | PRKCG (0.62) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Enzastaurin SCHEMBL678748 | 0.72 | PRKCG (1.00) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Enzastaurin SCHEMBL29356867 | 0.72 | PRKCG (1.00) | PRKCGPRKCBPRKCAPRKCEPRKCH | |
| Enzastaurin SCHEMBL29371538 | 0.72 | PRKCG (1.00) | PRKCGPRKCBPRKCAPRKCEPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096923-A1 | Methods For Diagnosing And Treating Diabetic Microvascular Complications | ELI LILLY AND COMPANY | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096923-A1 | Methods For Diagnosing And Treating Diabetic Microvascular Complications | FLT4, TEK, MAP3K13 | PRKCG 559/4885PRKCB 286/4885PRKCA 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.