Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.47 |
| ▸ | CES1 | P23141 | 6/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4493600 | 0.80 | CES2 (0.47) | CES2CES1NAAAKDM4EALDH1A1 | |
| SCHEMBL4489142 | 0.80 | CES2 (0.47) | CES2CES1NAAAKDM4EALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL1422472 | 0.79 | CES2 (0.49) | CES2CES1NAAATHRATHRB | |
| Hydrochloric Acid SCHEMBL6848392 | 0.79 | CES2 (0.46) | CES2CES1NAAAKDM4EALDH1A1 | |
| Bromide SCHEMBL11146660 | 0.79 | CES2 (0.46) | CES2CES1NAAAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8642216 | 0.79 | CES2 (0.46) | CES2CES1NAAAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8607225 | 0.76 | CES2 (0.47) | CES2CES1KDM4EALDH1A1POLB | |
| SCHEMBL27578934 | 0.75 | CES2 (0.50) | CES2CES1NAAAKAT8PPARA | |
| SCHEMBL1963286 | 0.75 | MAPT (0.45) | CES2CES1NAAAKDM4EALDH1A1 | |
| SCHEMBL29067602 | 0.74 | CES2 (0.45) | CES2CES1NAAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1925590-B1 | RESIN BASES WITH A LIGHT-RESISTANT TITANIC ACID COATING FILM | OTSUKA CHEMICAL CO LTD (JP) | 2011-03-23 | — | — | EP | disclosed |
| US-20090246555-A1 | Light-resistant titanic acid coating film and resin bases with the coating film | OTSUKA CHEMICAL CO., LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| EP-1925590-A1 | LIGHT-RESISTANT TITANIC ACID COATING FILM AND RESIN BASES WITH THE COATING FILM | Otsuka Chemical Co., Ltd. (JP) | 2008-05-28 | — | — | EP | disclosed |