Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 3/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17420726 | 0.94 | MAPT (0.47) | MAPTGAAPOLBCES2CES1 | |
| SCHEMBL9516289 | 0.84 | PPARA (0.51) | MAPTALDH1A1PPARARARBPLK1 | |
| SCHEMBL27804906 | 0.84 | PPARA (0.51) | MAPTALDH1A1PPARARARBPLK1 | |
| SCHEMBL29291134 | 0.83 | CES2 (0.43) | CES2CES1NAAACNR2PPARA | |
| SCHEMBL27832902 | 0.83 | RARB (0.45) | CES2CES1NAAACNR2PPARA | |
| SCHEMBL11699273 | 0.83 | CNR2 (0.43) | CES2CES1NAAAALDH1A1CNR2 | |
| SCHEMBL27825558 | 0.82 | PPARA (0.49) | MAPTALDH1A1PPARARARBPLK1 | |
| SCHEMBL11652259 | 0.81 | MAPT (0.42) | MAPTGAAPOLBCES2CES1 | |
| SCHEMBL8672001 | 0.81 | KAT8 (0.56) | MAPTGAAPOLBCES2CES1 | |
| SCHEMBL28428779 | 0.80 | CNR2 (0.43) | CES2CES1NAAAALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334727-A1 | POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES COMPRISING BENZOPHENONE-TYPE VOLTAGE STABILIZER | Borealis AG (AT) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010028721-A1 | POLYOLEFIN COMPOSITION FOR MEDIUM/HIGH/EXTRA HIGH VOLTAGE CABLES COMPRISING BENZOPHENONE-TYPE VOLTAGE STABILIZER | BOREALIS AG (AT) | 2010-03-18 | — | — | WO | disclosed |