Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197623 | 0.94 | F10 (0.82) | F10PTGS2MAPT | |
| SCHEMBL75696 | 0.84 | F10 (0.82) | F10MAPT | |
| SCHEMBL75697 | 0.84 | F10 (0.82) | F10MAPT | |
| SCHEMBL92852 | 0.84 | F10 (0.61) | F10PTGS2MAPTUSP2ALDH1A1 | |
| SCHEMBL85846 | 0.84 | F10 (0.83) | F10PTGS2MAPTUSP2ALDH1A1 | |
| SCHEMBL12795625 | 0.84 | F10 (0.83) | F10PTGS2MAPTUSP2ALDH1A1 | |
| SCHEMBL92851 | 0.84 | F10 (0.83) | F10PTGS2MAPTUSP2ALDH1A1 | |
| SCHEMBL5075423 | 0.84 | F10 (1.00) | F10MAPT | |
| SCHEMBL5078646 | 0.84 | F10 (1.00) | F10MAPT | |
| SCHEMBL5078066 | 0.84 | F10 (1.00) | F10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081814-A1 | Carbonyl Compounds Which Can be Used as Inhibitors of Coagulation Factor Xa | CEZANNE BERTRAM | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081814-A1 | Carbonyl Compounds Which Can be Used as Inhibitors of Coagulation Factor Xa | F2, F11, F12 | F10 4/4885PTGS2 714/4885MAPT 4368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.