Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.69 |
| ▸ | PGR | P06401 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | SHBG | P04278 | 3/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661457 | 1.00 | CYP19A1 (0.69) | CYP19A1PGRCYP3A4LMNAAR | |
| SCHEMBL20851687 | 1.00 | CYP19A1 (0.69) | CYP19A1PGRCYP3A4LMNAAR | |
| SCHEMBL3182567 | 1.00 | CYP19A1 (0.69) | CYP19A1PGRCYP3A4LMNAAR | |
| SCHEMBL11629995 | 1.00 | CYP19A1 (0.69) | CYP19A1PGRCYP3A4LMNAAR | |
| SCHEMBL22845080 | 1.00 | CYP19A1 (0.69) | CYP19A1PGRCYP3A4LMNAAR | |
| SCHEMBL11629999 | 1.00 | CYP19A1 (0.69) | CYP19A1PGRCYP3A4LMNAAR | |
| SCHEMBL11755439 | 0.90 | CYP19A1 (0.66) | CYP19A1PGRCYP3A4LMNAAR | |
| SCHEMBL6832274 | 0.88 | CYP19A1 (0.65) | CYP19A1PGRCYP3A4LMNAAR | |
| SCHEMBL4107677 | 0.86 | CYP19A1 (0.57) | CYP19A1PGRCYP3A4LMNAAR | |
| SCHEMBL16937732 | 0.85 | CYP19A1 (0.62) | CYP19A1PGRCYP3A4LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111593086-B | Method for reducing impurities in ethyldiketone 11a hydroxylation process by using mixed solvent | 湖北葛店人福药业有限责任公司 | 2023-05-05 | — | — | CN | claimed |
| EP-1504021-B1 | PROCESS FOR DEHYDROGENATION OF AZAANDROSTANE COMPOUNDS | RICHTER GEDEON VEGYESZET (HU) | 2006-07-12 | — | — | EP | claimed |
| EP-1504021-A1 | PROCESS FOR DEHYDROGENATION OF AZAANDROSTANE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2005-02-09 | — | — | EP | claimed |
| US-6762302-B2 | DEPROTONATION OF AZASTEROIDS USING CULTURES OF BIOCATALYSTS, OXIDOREDUCTASE ENZYMES, STABILIZERS, COMPLEXING AGENTS AND CHARGE TRANSFER COMPOUNDS, THEN INCUBATING | GEDEON RICHTER, LTD. (HU) | 2004-07-13 | — | — | US | claimed |
| WO-2003095472-A1 | PROCESS FOR DEHYDROGENATION OF AZAANDROSTANE COMPOUNDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-11-20 | — | — | WO | claimed |
| US-20030215902-A1 | Process for dehydrogenation of azaandros tane compounds | RICHTER GEDEON VEGYESZETI GYAR RT. | 2003-11-20 | — | — | US | claimed |
| US-5831104-A | Steroid intermediate products and method of their production | JENAPHARM GMBH (DE) | 1998-11-03 | — | — | US | claimed |
| WO-1997023498-A1 | 18-METHYL 16-METHYLENE 19-NOR PREGNANE DERIVATIVES AS PROGESTINS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION THEREOF | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1997-07-03 | — | — | WO | claimed |
| CN-119751531-A | Preparation method of levorotatory ethyl sterenedione | 浙江仙琚制药股份有限公司 | 2025-04-04 | — | — | CN | disclosed |
| US-11912738-B2 | Neuroactive steroids and their methods of use | SAGE THERAPEUTICS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912738-B2 | Neuroactive steroids and their methods of use | SAGE THERAPEUTICS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| CN-117402201-A | Preparation methods of desogestrel, etogestrel and intermediates thereof, and intermediates | 扬州奥锐特药业有限公司 | 2024-01-16 | — | — | CN | disclosed |
| US-20230322849-A1 | NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | SAGE THERAPEUTICS, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230322849-A1 | NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | SAGE THERAPEUTICS, INC. | 2023-10-12 | — | — | US | disclosed |
| US-3965138-A | Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3960896-A | Aryl ketals of polycyclic oxo compounds and processes | HOFFMANN-LA ROCHE INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3960895-A | Aryl ketals of polycyclic oxo compounds and processes | HOFFMANN-LA ROCHE INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3959322-A | Synthesis of 13-alkyl-gon-4-ones | Smith, Herchel (US) | 1976-05-25 | — | — | US | disclosed |
| US-3950358-A | ARYL KETALS OF 3,7-DIHYDROXY-11-OXO-DODEC-1-ENE | HOFFMANN-LA ROCHE INC. (US) | 1976-04-13 | — | — | US | disclosed |
| US-3948951-A | Aryl ketals of 1-chloro-4-oxo-pentane | HOFFMANN-LA ROCHE INC. (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322849-A1 | NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | NR3C2, MC2R, NR3C1 | CYP19A1 169/4885PGR 252/4885CYP3A4 929/4885 |
| US-11912738-B2 | Neuroactive steroids and their methods of use | NR3C2, MC2R, NR3C1 | CYP19A1 169/4885PGR 252/4885CYP3A4 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.