Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.80 |
| ▸ | CES1 | P23141 | 2/20 | 0.80 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.76 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.76 |
| ▸ | F3 | P13726 | 1/20 | 0.76 |
| ▸ | PNLIP | P16233 | 1/20 | 0.76 |
| ▸ | NOS2 | P35228 | 1/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.67 |
| ▸ | RELA | Q04206 | 3/20 | 0.67 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.56 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14240644 | 1.00 | CES2 (0.80) | CES2CES1PTPN1PTPN2F3 | |
| SCHEMBL2453965 | 0.89 | CES2 (1.00) | CES2CES1PTPN1PTPN2F3 | |
| SCHEMBL18687839 | 0.89 | CES2 (1.00) | CES2CES1PTPN1PTPN2F3 | |
| SCHEMBL29984730 | 0.89 | CES2 (1.00) | CES2CES1PTPN1PTPN2F3 | |
| SCHEMBL12313092 | 0.89 | CES2 (1.00) | CES2CES1PTPN1PTPN2F3 | |
| Oleanonic Acid SCHEMBL12337276 | 0.87 | PTPN2 (1.00) | CES2CES1PTPN1PTPN2F3 | |
| 3-Oxo-Erythrodiol SCHEMBL18688302 | 0.87 | CES2 (0.76) | CES2CES1PTPN1PTPN2F3 | |
| Oleanonic Acid SCHEMBL12200334 | 0.87 | PTPN2 (1.00) | CES2CES1PTPN1PTPN2F3 | |
| Oleanonic Acid SCHEMBL18688313 | 0.87 | PTPN2 (1.00) | CES2CES1PTPN1PTPN2F3 | |
| SCHEMBL17166004 | 0.87 | PTPN1 (0.85) | CES2CES1PTPN1PTPN2F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120316144-A1 | ANTIFUNGAL AGENT | ALLIANCE CO., LTD. (JP) | 2012-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316144-A1 | ANTIFUNGAL AGENT | ERG28, CYP51A1, LSS | CES2 2034/4885CES1 1457/4885PTPN1 4462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.