Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Dithiazanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | THRB | P10828 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | CTNNB1 | P35222 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7761426 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL29369795 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Iodide SCHEMBL139369 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Iodide SCHEMBL29393130 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL22877 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL77427 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Iodide SCHEMBL335663 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL29459605 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL13898198 | 0.99 | KMT2A (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL1567134 | 0.99 | KMT2A (1.00) | MEN1KMT2ANPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1018 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250025426-A1 | SYNERGISTIC TRANSPORT OF LIPOPHILIC AND HYDROPHILIC ACTIVE SUBSTANCES IN NANOPARTICLES | Karlsruher Institut für Technologie (DE) | 2025-01-23 | — | — | US | claimed |
| US-12173355-B2 | Nano-plasmonic molecular probes and methods of use | DUKE UNIVERSITY (US) | 2024-12-24 | — | — | US | claimed |
| US-20240401113-A1 | AMPLIFICATION SYSTEMS FOR NANO-PLASMONIC MOLECULAR PROBES AND METHODS THEREOF | DUKE UNIVERSITY | 2024-12-05 | — | — | US | claimed |
| US-20240402164-A1 | PLASMONIC CAGED NANOPLATFORMS AND METHODS THEREOF | DUKE UNIVERSITY | 2024-12-05 | — | — | US | claimed |
| EP-4444275-A1 | SYNERGISTIC TRANSPORT OF LIPOPHILIC AND HYDROPHILIC ACTIVE SUBSTANCES IN NANOPARTICLES | Karlsruher Institut für Technologie (DE) | 2024-10-16 | — | — | EP | claimed |
| US-20240156993-A1 | PLASMONICS SENSING NANOPLATFORMS FOR HUMAN STEM CELL APPLICATIONS AND METHODS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-05-16 | — | — | US | claimed |
| WO-2023104380-A1 | SYNERGISTIC TRANSPORT OF LIPOPHILIC AND HYDROPHILIC ACTIVE SUBSTANCES IN NANOPARTICLES | Karlsruher Institut für Technologie (DE) | 2023-06-15 | — | — | WO | claimed |
| EP-4190312-A1 | SYNERGISTIC TRANSPORT OF LIPOPHILIC AND HYDROPHILIC ACTIVE AGENTS INTO NANOPARTICLES | Karlsruher Institut für Technologie (DE) | 2023-06-07 | — | — | EP | claimed |
| EP-3646012-B1 | SERS-ACTIVE OPTO-FLUIDIC PHOTONIC CRYSTAL FIBER PROBE INCLUDING A BIOPSY NEEDLE AND METHOD USING THE PROBE | AGENCY SCIENCE TECH & RES (SG) | 2023-03-08 | — | — | EP | claimed |
| EP-4097249-A2 | PLASMONICS SENSING NANOPLATFORMS FOR HUMAN STEM CELL APPLICATIONS AND METHODS THEREOF | Duke University (US) | 2022-12-07 | — | — | EP | claimed |
| WO-1996022531-A1 | A BIOSPECIFIC MULTIPARAMETER ASSAY METHOD | SOINI ERKKI (FI) | 1996-07-25 | — | — | WO | claimed |
| WO-1994018552-A1 | MULTIPLEXED FLUORESCENCE DETECTOR SYSTEM FOR CAPILLARY ELECTROPHORESIS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1994-08-18 | — | — | WO | claimed |
| US-5324401-A | Multiplexed fluorescence detector system for capillary electrophoresis | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1994-06-28 | — | — | US | claimed |
| US-4728796-A | Method for ionization of polymers | MEDICAL COLLEGE OF WISCONSIN (US) | 1988-03-01 | — | — | US | claimed |
| US-4362645-A | Temperature indicating compositions of matter | AKZONA, INC. (US) | 1982-12-07 | — | — | US | claimed |
| US-4345470-A | All plastic disposable thermometer | AKZONA INCORPORATED (US) | 1982-08-24 | — | — | US | claimed |
| US-4339207-A | Temperature indicating compositions of matter | AKZONA INCORPORATED (US) | 1982-07-13 | — | — | US | claimed |
| US-4299727-A | Disposable reversible thermometer | AKZONA INCORPORATED (US) | 1981-11-10 | — | — | US | claimed |
| US-4232552-A | THERMOCHROMISM, DISPOSABLE THERMOMETERS | AKZONA INCORPORATED (US) | 1980-11-11 | — | — | US | claimed |
| US-3958991-A | PHOTOCONDUCTOR | EASTMAN KODAK COMPANY (US) | 1976-05-25 | — | — | US | claimed |