Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | THRB | P10828 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | CTNNB1 | P35222 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dithiazanine SCHEMBL22877 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL29369795 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Iodide SCHEMBL139369 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL29459605 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL77427 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Iodide SCHEMBL335663 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Iodide SCHEMBL29393130 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL142280 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL1598509 | 0.99 | KMT2A (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL13898198 | 0.99 | KMT2A (1.00) | MEN1KMT2ANPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3120392-A1 | TRANSPARENT ENERGY-HARVESTING DEVICES | Board of Trustees of Michigan State University (US) | 2017-01-25 | — | — | EP | claimed |
| WO-2015143038-A1 | TRANSPARENT ENERGY-HARVESTING DEVICES | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2015-09-24 | — | — | WO | claimed |
| EP-3857276-A1 | TRANSPARENT LUMINESCENT SOLAR CONCENTRATOR | Board Of Trustees Of Michigan State University (US) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020068670-A1 | TRANSPARENT LUMINESCENT SOLAR CONCENTRATOR | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2020-04-02 | — | — | WO | disclosed |
| US-20190350672-A1 | METHOD AND DEVICE FOR ENHANCED TRANSDERMAL VISUALIZATION OF MEDICAL DEVICES | VISIONARY MEDICAL THERAPIES INC (US) | 2019-11-21 | — | — | US | disclosed |
| US-9833144-B2 | Probes, methods of making probes, and methods of use | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-12-05 | — | — | US | disclosed |
| EP-3120392-A1 | TRANSPARENT ENERGY-HARVESTING DEVICES | Board of Trustees of Michigan State University (US) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015143038-A1 | TRANSPARENT ENERGY-HARVESTING DEVICES | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2015-09-24 | — | — | WO | disclosed |
| US-20120179029-A1 | PROBES, METHODS OF MAKING PROBES, AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-07-12 | — | — | US | disclosed |
| EP-1107057-A1 | Photographic colour filter array film | EASTMAN KODAK COMPANY (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-0610994-B1 | Photographic elements for producing blue, green and red exposure records of the same hue and methods for the retrieval and differentiation of the exposure records | KODAK LTD (GB) | 1997-12-10 | — | — | EP | disclosed |